Microbes in stem cell Research and Gene Therapy.
As we know Stem cells have the capacity of Regeneration and Proliferation which is a potential capacity of Cancer stem cell also. Sometime these cells not obey the normal Apoptosis signals hence a suicidal gene directly transduced by the help of Oncolytic Virus to eradicate these cancer stem cells which is called Virus vector transduction. In recent report it was observed that a leprosy bacterium helps to convert normal adult cells in to stem cells. Gut bacteria is the prime vector in case of colon cancer to activate intestinal stem cells. Virus also used as a vector for stem cell culture.
· Bacterial-modulated intestinal stem cell activation
· Leprosy Bacteria: turns adult cells into stem cells
· Virus as a vector for stem cell culture
· Gut bacteria : Role in colon Cancer